BernheimV1, Main, Exploration, bibRecord, 000C34

Cytogenetic studies on acute myelomonocytic leukaemia (M4) with eosinophilia

Identifieur interne : 000C34 ( Main/Exploration ); précédent : 000C33; suivant : 000C35

Cytogenetic studies on acute myelomonocytic leukaemia (M4) with eosinophilia

Auteurs : R. Berger [France] ; A. Bernheim [France] ; M. T. Daniel [France] ; F. Valensi [France] ; F. Sigaux [France] ; G. Flandrin [France]

Source :

Leukemia Research [ 0145-2126 ] ; 1985.

RBID : ISTEX:104747F309B0085E1FFF5F0FB1481782CF6216EB

English descriptors

Teeft :
- Abnormal, Abnormal clone, Abnormal eosinophils, Abnormal granules, Abnormal karyotypes, Abnormality, Acute leukemia, Acute myelomonocytic leukemia, Barium hydroxide, Bone marrow, Bone marrow cells, Bone marrow eosinophilia, Chromosome, Cytogenetic studies, Eosinophil, Eosinophilia, Favourable prognosis, Fragile sites, Granule, Inversion, Leukemia, M4eo, M4eo patients, Marrow, Mitoses, Monocytic, Monocytic cells, Myelomonocytic, Other abnormalities, Other cells, Peripheral blood, Present study.

Abstract

Abstract: Cytological and cytogenetic studies on 17 acute myelomonocytic leukemia with bone marrow eosinophilia (M4EO) are reported. Cytological criteria include an unusual high proportion of eosinophilic cells containing abnormal granules. Abnormal karyotypes have been found in 12 patients but chromosome 16 abnormalities were present in only 9. In two of them only one such mitose was detected whereas in 7 others inv(16)(p13q22) and/or del (16)(q22) clones were present. However in 16 cases normal karyotypes were also present. Other abnormal clones coexisted in three patients, suggesting that chromosome 16 abnormalities are not linked to a primary leukemogenic event. M4EO was found to be associated with a favourable prognosis.

Url:

https://api.istex.fr/document/104747F309B0085E1FFF5F0FB1481782CF6216EB/fulltext/pdf

DOI: 10.1016/0145-2126(85)90090-6

Affiliations:

Links toward previous steps (curation, corpus...)

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Le document en format XML

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<front><div type="abstract" xml:lang="en">Abstract: Cytological and cytogenetic studies on 17 acute myelomonocytic leukemia with bone marrow eosinophilia (M4EO) are reported. Cytological criteria include an unusual high proportion of eosinophilic cells containing abnormal granules. Abnormal karyotypes have been found in 12 patients but chromosome 16 abnormalities were present in only 9. In two of them only one such mitose was detected whereas in 7 others inv(16)(p13q22) and/or del (16)(q22) clones were present. However in 16 cases normal karyotypes were also present. Other abnormal clones coexisted in three patients, suggesting that chromosome 16 abnormalities are not linked to a primary leukemogenic event. M4EO was found to be associated with a favourable prognosis.</div>
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Serveur d'exploration Hippolyte Bernheim

Cytogenetic studies on acute myelomonocytic leukaemia (M4) with eosinophilia

Cytogenetic studies on acute myelomonocytic leukaemia (M4) with eosinophilia

Source :

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri